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Excerpt scheduled to appear in Appendix 1, 207 Acridones, as BCRP inhibitors, 304305, 305 Acute lymphocytic leukemia (ALL), 425 ABCB1 in, 318 and ABCC3 relevance, 133 ABCG2 expression in, 9798 ABCG2 in, 129130, 131 BCRP in, 131 pharmacogenetics of, 421422 prognostic impact of ABCC1 in, 131 Acute myeloid leukemia (AML), 316 and ABCC3 relevance, 133 ABCG2 in, 9798, 128, 129130 CAM-DR of, 334335 clinical trials with ABCB1 modulator, 125126 drug resistance in, 84 expression of ABCA3 in, 133 expression of BCRP in, 128 MDR-reversing agents in, 355 443 pediatric, 133 and P-gp expression, 122 P-gp inhibitors in, 244 pharmacogenetics of, 421, 424425 prognostic factors in, 317 Agarofuran sesquiterpenes, 205 Age, and ABCC-related activity, 59 Agosterol A as MRP modulator, 269270 structure of, 270 AIDS, pharmacogenetics of, 417, 423, 425426 Alcohol consumption, and aerodigestive tract cancers, 22 All-trans retinoic acid (ATRA), 28 ALSGGQ motif, 262 Alzheimers disease, 377378 Amino acids and ABC transporters, 54 uptake of, 388 Amiodarone, in clinical trials with ABCB1, 124 Amlodipine, and chloroquine accumulation, 214 Amoebic dysentery, 196 Anthracenic derivatives, in protozoan parasite resistance, 219 Anthracyclines and blood-brain brrier, 368 in clinical trials with ABCB1 modulator, 124, 125126, 127 extruded by BCRP, 292 lipophilic, 251 in metastatic breast cancer, 163 MRPs inhibited by, 264 and protection of ABC proteins, 122 Antibiotic resistance, bacterial ABC transporters responsible for, 183186, 185 Antibiotics.
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